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PRIME SOURCE LLC

Meso 4SC Select Herbicide

Meso 4SC Select is a selective pre- and post-emergent herbicide that controls weeds on turfgrass and ornamentals. During the critical seed germination and establishment phase, Meso 4SC can provide year-long control of troublesome weeds such as chickweed, henbit, and crabgrass.

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Meso 4SC Select Product Page
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01/10/26
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Meso 4SC Select, manufactured by Prime Source, is a mesotrione-based product known for its broad spectrum of weed control.

Mesotrione is also the active ingredient in the popular herbicide brand Tenacity. Meso 4SC Select contains the same formula and can provide excellent crabgrass control in residential yards. This is important because the EPA has recently banned MSMA (a go-to recommendation for crabgrass control) for homeowner or residential use.

Meso 4SC Select is easy to mix and apply and can kill treated weeds within 2 to 3 weeks of application. Use it when dealing with hard-to-control weeds like nutsedge, clover, crabgrass, barnyard grass, and more.

Tools Needed

This product can be applied with a pressurized hydraulic sprayer, high-volume handgun spray, hand-held pump sprayer, or backpack sprayer.

How to Use

Spraying Tenacity

  • Step 1: Determine how much Meso 4SC Select to use by measuring the square footage of the treatment area. Do this by measuring the treatment area's length and width in feet, then multiplying them together (length X width = square footage). The typical application rate is 4 to 8 oz. of Meso 4SC Select per 30 gallons of water per acre for large applications. For smaller areas and spot treatments, a half teaspoon of the product with 1.5 teaspoons of surfactant in 1 gallon of water will treat 1,000 sq. ft. Refer to the product label for specific application rates and restrictions.
  • Step 2: Fill a hand-pump sprayer halfway with water, and then add the required amount of Meso 4SC Select to the tank.  Replace the cap and agitate by shaking the sprayer. If needed, add the remaining water required and surfactant, then repeat agitation to ensure that the herbicide solution is thoroughly mixed.
  • Step 3: Apply Meso 4SC selectively to the target weed, being careful not to overapply or spray to the point of runoff. Use a fan spray nozzle setting for even coverage. Repeat application in 2 to 3 weeks for best results.

Where to Use

Meso 4SC Select is for use in and around turfgrass, including sod farms, commercial and residential turf, and ornamentals.

When to Use

Use during the growing season when unwanted weeds are growing on the property. The product is best applied when weeds are young and growing. It can also be applied as a fall and early spring pre-emergent.

Safety Information

Meso 4SC Select is safe for children and pets when applied according to the product label instructions. Always wear the proper personal protective equipment (PPE) when mixing and applying this product.

Pets and children should not be present during treatment and remain out of the treated areas until completely dried.

Special Considerations

Bentgrass, Poa annua, Kikuyugrass, Zoysiagrass, Seashore Paspalum, and Bermudagrass are sensitive to Meso 4SC Select applications. Avoid spraying these turf types unless control and/or injury can be tolerated. A surfactant is recommended with Meso 4SC Select to improve weed control and provide a better stick to the weeds' leaf surfaces.

More Information
Restricted Use No
Shipping Restrictions AK, AZ
Availability Online
Signal Word CAUTION
Keith's Pro Tip "Meso 4SC Select is best used with a surfactant such as Alligare 90. Keep an eye on your weeds because it may take a 2nd application. Remember that you will not see results overnight. Do not apply the Meso 4SC. Select more than the label recommends, and make sure that outside temperatures are no higher than 80 degrees Fahrenheit."
Time to Kill Weeds treated with Meso 4SC will die off within 3 weeks from the application.
Chemical Type Herbicide
Formulation Suspended Concentrate
Application Methods Spot Treatment
Product Drawbacks Meso 4SC Select Herbicide can temporarily whiten or bleach desired turf but white grass tips can be mowed off.
Active Ingredient Mesotrione 40.0%
Application Equipment Hose End Sprayer, Pump Sprayer
Mix Rate Mix 1/3 ounce (0.5 teaspoons) of Meso 4SC Select in 1 gallon of water for spot treatments. For more specific application rates please refer to the label.
Use Sites Outdoors
Yield If used at the maximum rate of application per acre to St. Augustinegrass each 8-ounce container of Meso 4SC Select Herbicide will treat an estimated 2 acres.
EPA Registration No. 89442-33
Shelf Life Meso 4SC Select Herbicide will last up to 3 years when stored away from heat and flame. Do not store near seed, fertilizers, or foodstuffs. Can be stored at temperatures as low as minus 20°F.
Comparable Products Tenacity Herbicide
Children or pets? No
Property Characteristics None
AvailabilityOnline
Restricted UseNo
BrandPRIME SOURCE LLC
Keith's Pro Tips"Meso 4SC Select is best used with a surfactant such as Alligare 90. Keep an eye on your weeds because it may take a 2nd application. Remember that you will not see results overnight. Do not apply the Meso 4SC. Select more than the label recommends, and make sure that outside temperatures are no higher than 80 degrees Fahrenheit."
Product DrawbacksMeso 4SC Select Herbicide can temporarily whiten or bleach desired turf but white grass tips can be mowed off.
Target PestsKentucky bluegrass, centipedegrass, buffalograss, tall fescue, perennial ryegrass, fine fescue and St. Augustine grass (grown for sod) to control Annual Bluegrass, Barnyardgrass, Buckhorn Plantain, Canada Thistle, Carpetweed, Catsear Dandelion, Common Chickweed, Common Dandelion, Common Lambsquarters, Common Purslane, Creeping Bentgrass, Curly Dock, Florida Betony, Florida Pusley, Galinsoga, Goosgrass, Ground Ivy, Healall, Henbit, Lambsquarters, Large Crabgrass, Large Hop Clover, Lawn Burweed, Marestail, Mouseear Chickweed, Mouseear Chickweed, Nimblewill, Oxalis, Pale Smartweed, Pennsylvania Smartweed, Persian Speedwell, Purslane Speedwell, Redroot Pigweed, Shepherd's Purse, Smooth Crabgrass, Smooth Pigweed, Southern Crabgrass, Sowthistle, Swinecress, Tufted Lovegrass, Verbena, White Clover, Wild Carrot, Wild Violet, Windmillgrass, Yellow Foxtail, and Yellow Nutsedge.
Application EquipmentHose End Sprayer, Pump Sprayer
Application MethodsSpot Treatment
Active IngredientMesotrione 40.0%
Product TypeHerbicide
FormulationSuspended Concentrate
Application RateMix 1/3 ounce (0.5 teaspoons) of Meso 4SC Select in 1 gallon of water for spot treatments. For more specific application rates please refer to the label.
Shelf LifeMeso 4SC Select Herbicide will last up to 3 years when stored away from heat and flame. Do not store near seed, fertilizers, or foodstuffs. Can be stored at temperatures as low as minus 20°F.
YieldIf used at the maximum rate of application per acre to St. Augustinegrass each 8-ounce container of Meso 4SC Select Herbicide will treat an estimated 2 acres.
Use SitesOutdoors
Time to KillWeeds treated with Meso 4SC will die off within 3 weeks from the application.
Comparable ProductsTenacity Herbicide
EPA Registration #89442-33

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