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Weed Pro Glyphosate 41%
Weed Pro Glyphosate 41% is a professional non-selective weed killer that delivers fast reliable control of tough weeds and grasses in and around ornamental landscapes, buildings, and in brick and gravel driveways. It becomes rainproof in just 2 hours.
01/02/26
Weed Pro Glyphosate 41%, manufactured by Southern Ag, is a trusted and powerful non-selective herbicide concentrate known for killing various broadleaf weeds and grasses down to the roots, making it a top choice for homeowners, landscapers, and professionals who want dependable weed control that works quickly and keeps working.
The active ingredient, glyphosate 41.0%, works by shutting down an essential enzyme plants need to grow. Once absorbed, the plant slowly starves and dies from the top all the way down to the root system. Because it is systemic rather than merely contact-killing, it’s highly effective against both annual and perennial weeds and unwanted grasses such as poison ivy, annual bluegrass, trumpetcreeper, and more.
Weed Pro Glyphosate 41% is a high-strength, professional post-emergent herbicide that kills weeds and grasses thoroughly all the way to the roots, making it ideal for clearing overgrown areas, preparing sites for new planting, and maintaining tidy landscapes. Planting may occur the next day after application, which is good because it minimizes downtime, keeps projects on schedule, and allows quick replanting without long wait periods after weed control.
Tools Needed
You will need to make applications with a handheld pump sprayer, hose-end sprayer, backpack sprayer, or hand-trigger sprayer.
A sprayer with a tank made of plastic, aluminum or stainless steel must be used.
How to Use
- Step 1: Determine how much Weed Pro Glyphosate 41% to use by measuring the square footage of the treatment area. Find the square footage by measuring the treatment area's length and width in feet, then multiply them together (length X width = square footage). When using a tank sprayer for general weed control on annual weeds, mix 1 to 1 1/2 fluid ounces (3 tablespoons) of Weed Pro Glyphosate 41% per gallon of water, which will treat approximately 300 square feet (about a 10 x 30 ft. area). For hard-to-control weeds, perennials, brush, or lawn renovation, increase the rate to 2 to 2 1/2 fluid ounces (5 tablespoons) of product per gallon of water, which will treat approximately 300 square feet (about a 10 x 30 ft. area). If you’re using a hand-trigger sprayer, mix 1 teaspoon of product per 24 fluid ounces of water for general weed control, or 2 teaspoons of product per 24 fluid ounces of water for tougher weeds. Hand-trigger sprayers are best for spot treatments or treating individual weeds rather than large areas.
- Step 2: Fill the sprayer tank with half the amount of water, add the proper amount of product, and pour in the remaining half of the water. Close the tank lid and shake until well-mixed. For best results, use within two weeks after mixing with water.
- Step 3: Spray the top and bottom of the weed leaves until wet, but not to the point of runoff. For brush control, if the plants are taller than 5 feet, cut back and spray regrowth. Be aware that turf or other desirable plants or groundcovers may be damaged if undried spray is tracked from adjacent treated areas. If re-application is necessary, wait until new growth appears.
Where to Use
Weed Pro Glyphosate 41% can be used around driveways, walkways, fences, trees, flower beds, trees, shrubs and other areas of yards. This product may also be used on large areas to kill existing turfgrasses prior to sodding or reseeding, and for weed control in garden plots prior to planting.
When to Use
It may be applied anytime weeds are actively growing. Treated weeds may begin to wilt within a few hours, but complete kill may require 1 to 2 weeks. Mature weeds in advanced growth stages may require up to 4 weeks for complete kill. For best results, apply when weeds are small and before seedheads have formed.
Spray when the air is calm and make sure that spray does not contact leaves, green stems or exposed roots of plants you do not want to kill.
For best results during lawn renovations, apply in spring or fall when daytime temperatures are at least 60 degrees Fahrenheit and the weeds or turfgrass to be removed are actively growing.
Safety Information
Weed Pro Glyphosate 41% is safe to use around children and pets when applied according to the product label instructions. Always wear the proper personal protective equipment (PPE) when mixing and applying this product.
Keep people and pets out of treated areas until sprays have dried.
Special Considerations
Do not use or store spray mixtures of this product in galvanized steel or unlined steel sprayers, or apply through any type or irrigation system or with a sprinkler can.
| Restricted Use | No |
|---|---|
| Availability | Online |
| Signal Word | CAUTION |
| Keith's Pro Tip | "If necessary, use cardboard or plastic to prevent spray from contacting valuable plants. By doing this you help to avoid unwanted drift and better protect desired foliage." |
| Time to Kill | Weed Pro Glyphosate 41% will control weeds within 3-7 days or more. |
| Chemical Type | Herbicide |
| Formulation | Emulsifiable Concentrate (EC) |
| Application Methods | Spot Treatment |
| Product Drawbacks | DO NOT use for spot weed control in lawns. |
| Active Ingredient | Glyphosate 41.0% |
| Application Equipment | Backpack Sprayer, Hose End Sprayer, Pump Sprayer |
| Mix Rate | When using a tank sprayer for general weed control on annual weeds, mix 1 to 1 1/2 fluid ounces (3 tablespoons) of Weed Pro Glyphosate 41% per gallon of water, which will treat approximately 300 square feet (about a 10 x 30 ft. area). For hard-to-control weeds, perennials, brush, or lawn renovation, increase the rate to 2 to 2 1/2 fluid ounces (5 tablespoons) of product per gallon of water, which will treat approximately 300 square feet (about a 10 x 30 ft. area). If you’re using a hand-trigger sprayer, mix 1 teaspoon of product per 24 fluid ounces of water for general weed control, or 2 teaspoons of product per 24 fluid ounces of water for tougher weeds. |
| Use Sites | Outdoors |
| Yield | A 16 oz bottle of Weed Pro Glyphosate 41% will cover approximately 3,150 to 4,800 square feet when mixed at 1 to 1½ oz per gallon for general weed control, and about 1,950 to 2,400 square feet when mixed at 2 to 2½ oz per gallon for hard-to-control weeds. A 32 oz bottle will treat roughly 6,300 to 9,600 square feet at the lower rate and 3,900 to 4,800 square feet at the higher rate. A 1-gallon container (128 oz) provides the most coverage, treating approximately 25,500 to 38,400 square feet for general weeds or 15,300 to 19,200 square feet for tough weeds, based on an application rate of 300 square feet per finished gallon of spray. |
| EPA Registration No. | 62719-495-829 |
| Shelf Life | Weed Pro Glyphosate 41% will last for 3 years when stored in a dry, clean area. |
| Comparable Products | Eraser 41% Glyphosate, Quali-Pro Glyphosate Plus Herbicide, and Glyphosate 4 Plus Weed Killer Concentrate. |
| Availability | Online |
| Restricted Use | No |
| Brand | SOUTHERN AGRICULTURAL PRODUCTS |
| Keith's Pro Tips | "If necessary, use cardboard or plastic to prevent spray from contacting valuable plants. By doing this you help to avoid unwanted drift and better protect desired foliage." |
| Product Drawbacks | DO NOT use for spot weed control in lawns. |
| Target Pests | Alder, Annual Bluegrass, Annual Ryegrass, Bahiagrass, Barnyardgrass, Bermudagrass, Beggarweed, Black Medic, Blackberry, Blue Toadflax, Broadleaf Plantain, Bromegrass, Bur Clover, Canada Thistle, Cherry species, Chickweed, Common Groundsel, Common Plantain, Common Ragweed, Crabgrass, Creeping Beggarweed, Creeping Bentgrass, Creeping Charlie, Curlydock, Dallisgrass, Dandelion, Dewberry, Diffuse Lovegrass, Dogfennel, Elderberry, False Dandelion, Fescue, Field Bindweed, Field Pennycress, Field Sandbur, Filaree, Florida Pusley, Foxtail, Fiddleneck, Garden Spurge, Henbit, Honeysuckle, Johnsongrass, Kentucky Bluegrass, Knotweed, Kudzu, Lambsquarters, Little Bittercress, London Rocket, Maidencane, Mallow, Mayweed, Mouseear, Multiflora Rose, Nimblewill, Nutsedge, Oak, Oleander, Orchardgrass, Oxalis, Pennywort, Pennsylvania Smartweed, Perennial Ryegrass, Poison Ivy, Poison Oak, Primrose, Prickly Lettuce, Prostrate Spurge, Puncturevine, Purple Nutsedge, Quackgrass, Ragweed, Raspberry, Red Clover, Redroot Pigweed, Sandbur, Shepardspurse, Smooth Bromegrass, Smooth Catsear, Smooth Pigweed, Spotted Spurge, St. Augustinegrass, Sumac, Tall Fescue, Tansy Mustard, Tansy Ragwort, Timothy, Torpedograss, Trumpetcreeper, Vaseygrass, White Clover, Whitetop, Wild Barley, Willow, Yellow Nutgrass, and Zoysiagrass. |
| Application Equipment | Backpack Sprayer, Hose End Sprayer, Pump Sprayer |
| Application Methods | Spot Treatment |
| Active Ingredient | Glyphosate 41.0% |
| Product Type | Herbicide |
| Formulation | Emulsifiable Concentrate (EC) |
| Application Rate | When using a tank sprayer for general weed control on annual weeds, mix 1 to 1 1/2 fluid ounces (3 tablespoons) of Weed Pro Glyphosate 41% per gallon of water, which will treat approximately 300 square feet (about a 10 x 30 ft. area). For hard-to-control weeds, perennials, brush, or lawn renovation, increase the rate to 2 to 2 1/2 fluid ounces (5 tablespoons) of product per gallon of water, which will treat approximately 300 square feet (about a 10 x 30 ft. area). If you’re using a hand-trigger sprayer, mix 1 teaspoon of product per 24 fluid ounces of water for general weed control, or 2 teaspoons of product per 24 fluid ounces of water for tougher weeds. |
| Shelf Life | Weed Pro Glyphosate 41% will last for 3 years when stored in a dry, clean area. |
| Yield | A 16 oz bottle of Weed Pro Glyphosate 41% will cover approximately 3,150 to 4,800 square feet when mixed at 1 to 1½ oz per gallon for general weed control, and about 1,950 to 2,400 square feet when mixed at 2 to 2½ oz per gallon for hard-to-control weeds. A 32 oz bottle will treat roughly 6,300 to 9,600 square feet at the lower rate and 3,900 to 4,800 square feet at the higher rate. A 1-gallon container (128 oz) provides the most coverage, treating approximately 25,500 to 38,400 square feet for general weeds or 15,300 to 19,200 square feet for tough weeds, based on an application rate of 300 square feet per finished gallon of spray. |
| Use Sites | Outdoors |
| Time to Kill | Weed Pro Glyphosate 41% will control weeds within 3-7 days or more. |
| Comparable Products | Eraser 41% Glyphosate, Quali-Pro Glyphosate Plus Herbicide, and Glyphosate 4 Plus Weed Killer Concentrate. |
| EPA Registration # | 62719-495-829 |
*Price does not include freight. We guarantee our rate plus shipping will be less than anyone else's price.




