• Call (800) 479-6583
  • Mon-Fri 8am-5pm
  • |
  • Sat 9am-5pm

Warfarinwarfarin chemistry

When there is a rat or mouse infestation afoot, rodenticide baits play a large role in controlling the population. Modern baits and formulations deliver an affordable and generally safe method of eliminating rat and mouse infestations as part of an integrated pest management strategy. However, this wasn’t always the case. The active ingredient which revolutionized the industry when it comes to effective rat poisons is warfarin.

Solutions Pest & Lawn has a variety of rodenticides in stock which are based with warfarin. On this page, you can learn more about warfarin and its origin, how it works and you can also shop the warfarin contained products we have in our inventory.

What is Warfarin?

Warfarin is known as a anticoagulant or blood thinner. Initially used in humans as a blood thinner to prevent blood clots, the substance then became a popular active ingredient in rat poisons. Warfarin revolutionized the rodent control business when it first appeared on the market in 1950. What made warfarin stand out was that it was safer to use than the highly toxic rodenticides used at that time (i.e., strychnine and zinc phosphide).

Warfarin has proved to be an ideal rodenticide in that its effect is cumulative, with the need for very low doses making bait-shyness and bait-dislike in rodent less likely.

Warfarin is used for controlling rats and house mice in and around homes, animal and agricultural premises, and commercial and industrial sites. It is odorless and tasteless and effective in very low dosages.

Warfarin comes in water soluble, ready-to-use bait, concentrate, powder, liquid concentrate, nylon pouch, coated talc and dust formulations. The compound also comes in mixed formulations with pindone, calciferol, and sulphaquinoxaline. It is considered compatible with other rodenticides.

In recent years there has been increasing cases of rodents developing a resistance to the effects of warfarin based products and thus “second-generation anticoagulants” were created to address the resistance.

How Warfarin Works

Warfarin kills rodents through affecting the rodent’s blood by thinning it, reducing the ability of blood to clot so that exposed rodents bleed internally and die.  Eventually the blood ceases to clot and permeates the artery walls. The rodent dies of multiple causes related to internal hemorrhaging.

Warfarin is highly water soluble, and readily bioavailable. So it can easily be dissolved and used by the body. Warfarin starts taking effect within 24 hours, but can take 3-5 days for the full effect to be realized.

View our selection of warfarin formulated products below. For more information about warfarin or other active ingredients in our rodenticides, please call us with your questions at 800-479-6583 or email us at askapro@solutionsstores.com

Where is Warfarin used?

Warfarin can successfully be used to control significant rodent infestations such as Norway rats, roof rats, mice, field rodents, opossums, and raccoons. It can be applied inside and outside of industrial buildings and homes, in outdoor alleys, port terminals, sewers, farmhouses, grain stores, factories, fields, and transport vehicles such as trains, ships, and aircraft.


In most areas, a child-proof and tamper-resistant bait station is required by law to avoid accidental poisoning of humans and nontargeted animals.


Is Warfarin Safe To Use?

Warfarin is regarded as one of the safest rodenticides by the EPA. This is largely due to two key characteristics of the compound. First, the delayed effect provides a large window for medical intervention in cases of accidental ingestion by a child or pet. Secondly, warfarin is rapidly metabolized and excreted from the body. The half-life, or the time required for the warfarin load in the body to decrease by one half, is about 42 hours. Warfarin is also used in humans, under the trade name Coumadin, to prevent blood clots and strokes. Most people who undergo surgeries such as coronary by-pass or joint replacements, take Coumadin for clot prevention. By contrast, the second-generation anticoagulants are not readily metabolized.


However, as safe as warfarin may be, measures should be taken to keep the poison away from children and pets. Gloves should be worn during application, make sure to wash hands after handling the bait, and avoid all contact with the mouth. Do not allow the bait to contaminate food or water supplies. In case of accidental swallowing, call the Center for Poison Control and a doctor immediately. If accidently ingested, it is required to be prolonged treatment with Vitamin K1 is required to recover from poisonings.


Learn more about rodent control by visiting our rats and mice control page!

Contact Us