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VPG
Hi-Yield Killzall Weed & Grass Killer
Hi-Yield Killzall Weed & Grass Killer is a post-emergent herbicide that effectively eliminates weeds and grasses down to the root within several weeks. This broad-spectrum product becomes rain-fast within 2 hours after application, helping to lessen the amount of Hi-Yield Killzall Weed & Grass Killer used.
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Hi-Yield Killzall product page
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Price as of
09/16/25
09/16/25
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Hi-Yield Killzall Weed & Grass Killer, manufactured by VPG, is an easy-to-mix herbicide designed to control a wide variety of annual or perennial weeds in residential and commercial lawns. It is ideal for preparing large sites for lawn renovation and edging landscapes.
This super concentrate product contains glyphosate, a double-surfactant ultra formulation that immediately dries on plants to start working quickly. Once applied, Hi-Yield Killzall Weed & Grass Killer will systemically prevent the production of certain substances found within plants, leading to withering and yellowing of treated foliage.
As a non-selective herbicide, Hi-Yield Killzall Weed & Grass Killer will eliminate any plant it touches but will not reside in the soil. As a result, neighboring plants and foliage that have not been treated will not be harmed or cause the soil to become sterilized.
Tools Needed
You will need a backpack or handheld pump sprayer. We recommend using a handheld pump sprayer for direct treatment of targeted weeds.
How to Use
- Step 1: Determine how much Hi-Yield Killzall Weed & Grass Killer to use by measuring the square footage of the treatment area. To find this, measure the length and width of the treatment area in feet and multiply them together (length X width = square footage). For best results, apply 2.5 oz. (5 tbs.) of Hi-Yield Killzall Weed & Grass Killer per 1 gallon of water per 300 sq. ft. Refer to the label for specific foliage application rates.
- Step 2: To mix, you will need to fill your sprayer with half the measured water, add the appropriate amount of product, and fill the sprayer the rest of the way with the remaining water. Close the sprayer's lid and shake until the mixture is even.
- Step 3: Adjust the sprayer to a low fan setting. Directly spray the top of targeted weeds or perform a spot treatment to avoid spraying desired foliage. Once your foliage has been treated, be careful not to mow, cut, or disturb treated vegetation for at least seven days following application.
Where to Use
Use Hi-Yield Killzall Weed & Grass Killer near fences, in paths, patios, sidewalks, curbs, and driveways, around ornamental trees, shrubs, flower beds and plantings, landscapes, desert landscapes, rock gardens, around buildings, fruit, nut trees or grapevines.
This product should not be applied on or around edible feed or food crops.
When to Use
It is ideal to use when preparing areas for landscaping, such as trimming or edging. This product may also be applied when weeds are actively growing, typically this will be in the spring or summer. Appropriate weather conditions to perform this application should be on warm sunny days around 60 degree Fahrenheit when rain or winds are not forecasted within 24 hours after treatment.
Safety Information
Hi-Yield Killzall Weed & Grass Killer is safe to use around children or pets when applied according to the labels instructions. Always wear the appropriate personal protective equipment (PPE) when mixing or applying this product.
If Hi-Yield Killzall Weed & Grass Killer is used to control weeds around fruit, nut trees or grapevines, wait 21 days before eating the fruit or nut trees.
Special Consideration
Hard-to-kill weeds may require a second application if not completely dead within 4 weeks after application.
Treated areas can be planted 1 day after the Hi-Yield Killzall Weed & Grass Killer application.
| Availability | Online |
| Restricted Use | No |
| Shipping Restrictions | 16 Ounce: AK, CA, CT, HI, IN, ME, MI, NY, OR, RI, SC, VT 1 Gallon: AK, CA, CT, HI, IN, MI, NY, OR, RI, SC, VT 32 Ounce: AK, CA, CT, HI, IN, ME, MI, NY, OR, RI, SC, VT |
| Brand | VPG |
| Keith's Pro Tips | "As a non-selective herbicide, Hi-Yield Killzall Weed & Grass Killer will harm any foliage it comes into with. During spray applications, you can protect desirable plants and vegetation with plastic or cardboard. If desirable plants are accidentally sprayed, immediately wash desirable plants thoroughly with plenty of clean water." |
| Product Drawbacks | Hi-Yield Killzall Weed & Grass Killer is not recommended for spot weed control in lawns since this product eliminates all green plants, including lawns. |
| Target Pests | Annual Weeds And Grasses: Annual Ryegrass, Annual Bluegrass, Barnyardgrass, Beggarweed, Black Medic, Blue Medic, Blue Toadflax, Brassbuttons, Blue Mustard, Bromegrass, Bur Clover, Buttercup, Cheeseweed, Chickweed, Clover, Common Groundsel, Common Lambsquarters, Common Plantain, Common Ragweed, Crabgrass, Creeping Beggarweed, Diffuse Lovegrass, Dog Fennel, Evening Primrose, False Dandelion, Fall Panicum, Fennel, Fiddleneck, Field Pennycress, Field Sandbur, Filaree, Florida Pusley, Foxtail, Garden Spurge, Goosegrass, Green Foxtail, Hemp Sesbania, Henbit, Horseweed/Marestail, Ironweed, Knotweed, Lambsquarter, Little Bitter Cress, London Rocket, Maiden Cane, Mallow, Mayweed, Mouseear Chickweed, Oxalis, Pennsylvania Smartweed, Pennywort, Pigweed, Prickly Lettuce, Prostrate Spurge, Puncture, Purslane, Redroot Pigweed, Sandspur, Shepherdspurse, Smartweed, Smooth Cat’s Ear, Smooth Pigweed, Sowthistle, Spotted Spurge, Sprangletop, Spurges, Tansy Mustard, Tansy Ragwort, Teaweed, Texas Panicum, Tumble Mustard, Velvetleaf, Wild Geranium*, Witchgrass, Wild Mustard, Yellow Nutgrass, Yellow Oxalis, and many other Annual Grasses and Weeds. Perennial Weeds, Grasses, Brush And Hard To Kill Weeds: Alder, Artichoke Thistle, Bahiagrass, Barnyardgrass, Bentgrass, Bermudagrass, Blackberries, Bluegrass, Broadleaf Plantain, Brownseed Paspalum, Buckhorn Plantain, Bull Thistle, Canada Thistle, Cattail, Ceanothus, Centipedegrass, Cherry, Cocklebur, Cogongrass, Common Mullein, Common Ragweed, Coralbead, Coyote Brush, Creeping Bentgrass, Creeping Charlie, Creeping Lantana, Curly Dock, Dallisgrass, Dandelion, Dewberry, Dog Fennel, Elderberry, False Dandelion, Fescue Species, Field Bindweed, Guineagrass, Hairy Crabgrass, Honeysuckle, Horsenettle, Horseradish, Iceplant, Johnsongrass, Kentucky Bluegrass, Kikuyugrass, Knapweed, Knawel, Kudzu, Lantana, Milkweed, Mouseear Chickweed, Multiflora Rose, Nimblewill, Nutgrass (Nutsedge), Oak Species, Oldenlandia, Orchardgrass, Oxalis*, Pampasgrass, Pennywort, Perennial Ryegrass, Plantain, Poison Oak, Poison Ivy, Poison Hemlock, Primrose, Purple Cudweed*, Purple Nutsedge, Quackgrass, Quaking Aspen, Ragweed, Raspberry, Red Clover, Smooth Bromegrass, Sourdock, Sowthistle, St. Augustinegrass, Sumac, Tall Fescue, Tansy, Ragwort, Thistle, Timothy, Torpedograss, Trumpetcreeper, Vaseygrass, Virginia Creeper, White Clover, Whitetop, Wild Barley, Wild Blackberry, Wild Carrot, Wild Morning-glory, Wild Oats, Wild Sweet Potato, Willow, Yarrow, Yellow Nutgrass, Yellow Starthistle, Zoysia and many other types of perennial weeds, grasses and brushes - even hard to kill types. |
| Application Equipment | Backpack Sprayer, Pump Sprayer |
| Application Methods | Spot Treatment |
| Active Ingredient | Glyphosate 41.0% |
| Product Type | Herbicide |
| Formulation | Emulsifiable Concentrate (EC) |
| Application Rate | For lawn renovation, use 2.5 oz. of product per gallon of water per 300 sq. ft. To control brush or vines, cut plants taller than 5 feet and spray the regrowth. For vines growing up a pole, fence, or mature tree trunk cut the vines until they are at height of 3 or 4 feet and spray thoroughly covering remaining line. For stump treatment, cut the stump close to the soil surface and make 4 to 5 nail holes into the stump then flood the stump with undiluted product. Refer to the label for specific rates and foliage to be treated. |
| Shelf Life | Hi-Yield Killzall Weed & Grass Killer will last up to 5 years when stored in a cool, dry place inaccessible to children or pets, and away from sources of heat or open flame. |
| Yield | One gallon of Hi-Yield Killzall Weed & Grass Killer will treat 25,600 sq. ft. (approximately the size of 12 tennis courts). |
| Use Sites | Outdoors |
| Time to Kill | Hi-Yield Killzall Weed & Grass Killer will remove hard-to-kill weeds within 4 weeks after first application. |
| Comparable Products | Eraser 41% Glyphosate, Gly Pho-Sel Pro, Ranger Pro |
| Use Caution With | Bentgrass, Bermudagrass, Kentucky Bluegrass, Fescue, Fine, Fescue, Tall, Kikuyugrass, Ryegrass, St Augustine, Zoysiagrass |
| Incompatible Home Siding | Brick, Hardie Plank, Stone Veneer, Stucco, Wood, Vinyl |
| EPA Registration # | 7401-451 |
| Restricted Use | No |
|---|---|
| Shipping Restrictions | AK, CA, CT, HI, IN, MI, NY, OR, RI, SC, VT |
| Availability | Online |
| Signal Word | CAUTION |
| Keith's Pro Tip | "As a non-selective herbicide, Hi-Yield Killzall Weed & Grass Killer will harm any foliage it comes into with. During spray applications, you can protect desirable plants and vegetation with plastic or cardboard. If desirable plants are accidentally sprayed, immediately wash desirable plants thoroughly with plenty of clean water." |
| Time to Kill | Hi-Yield Killzall Weed & Grass Killer will remove hard-to-kill weeds within 4 weeks after first application. |
| Chemical Type | Herbicide |
| Formulation | Emulsifiable Concentrate (EC) |
| Application Methods | Spot Treatment |
| Product Drawbacks | Hi-Yield Killzall Weed & Grass Killer is not recommended for spot weed control in lawns since this product eliminates all green plants, including lawns. |
| Active Ingredient | Glyphosate 41.0% |
| Application Equipment | Backpack Sprayer, Pump Sprayer |
| Mix Rate | For lawn renovation, use 2.5 oz. of product per gallon of water per 300 sq. ft. To control brush or vines, cut plants taller than 5 feet and spray the regrowth. For vines growing up a pole, fence, or mature tree trunk cut the vines until they are at height of 3 or 4 feet and spray thoroughly covering remaining line. For stump treatment, cut the stump close to the soil surface and make 4 to 5 nail holes into the stump then flood the stump with undiluted product. Refer to the label for specific rates and foliage to be treated. |
| Use Sites | Outdoors |
| Yield | One gallon of Hi-Yield Killzall Weed & Grass Killer will treat 25,600 sq. ft. (approximately the size of 12 tennis courts). |
| EPA Registration No. | 7401-451 |
| Shelf Life | Hi-Yield Killzall Weed & Grass Killer will last up to 5 years when stored in a cool, dry place inaccessible to children or pets, and away from sources of heat or open flame. |
| Comparable Products | Eraser 41% Glyphosate, Gly Pho-Sel Pro, Ranger Pro |
| Children or pets? | No |
| Property Characteristics | None |
*Price does not include freight. We guarantee our rate plus shipping will be less than anyone else's price.